Five-Minute Orville: "Old Wounds"

[Zeke]

The supreme irony is that they also got together on the show. They had an office romance while making a whole show about how bad an idea that is!

Seems to happen a lot in Hollywood. My personal favourite example, for its severe twistiness, is Michael C. Hall and Jennifer Carpenter on Dexter. They played Dexter and Deb, who grew up thinking they were blood siblings -- neither knew that Dex was adopted until Season 1 of the show -- and the actors got married. Then they got divorced. And then the show had Deb fall in love with Dex! It must've been even more awkward on set than it was in-universe. (Mercifully, that storyline was strangled in its crib when Deb found out Dex was a serial killer -- the person she loved was his "normal" persona, and now she knew he'd been faking that all his life. Still creepy though.)